New Strategies in Ewing Sarcoma: Lost in Translation?
نویسندگان
چکیده
منابع مشابه
New strategies in ewing sarcoma: lost in translation?
Ewing sarcoma is the second most common pediatric malignant bone tumor. Aggressive multimodality therapy has led to an improvement in outcomes, particularly in patients with localized disease. However, therapy-related toxicities are not trivial, and the prognosis for patients with relapsed and/or metastatic disease continues to be poor. In this article, we outline some of the promising therapie...
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New Strategies in Ewing’s Sarcoma: Lost in Translation? Running title: New Strategies in Ewing’s Sarcoma Fernanda I. Arnaldez, M.D., and Lee J. Helman, M.D. Pediatric Oncology Branch, National Cancer Institute, National Institutes of Health Bethesda, MD Corresponding Author Fernanda I. Arnaldez, MD Assistant Clinical Investigator Center for Cancer Research NCI/NIH 10 Center Drive Room 1W-3816 B...
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MicroRNAs (miRs) have emerged recently as important regulators of gene expression in the cell. Frequently dysregulated in cancer, miRs have shed new light on molecular mechanisms of oncogenesis, and have generated substantial interest as biomarkers, and novel therapeutic agents and targets. Recently, a number of studies have examined miR biology in Ewing sarcoma. Findings indicate that alterati...
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این تحقیق به بررسی استراتژیهای بکاررفته توسط مترجمین مختلف در ترجمه واژه های فرهنگی خاص در ترجمه فارسی به انگلیسی قانون مدنی و قانون اساسی جمهوری اسلامی ایران میپردازد.این تحقیق بر اساس نظریه پیتر نیومارک صرت گرفته است. در این تحفیق واژه های فرهنگی خاص اقتباس شده و پس از مقایسه با متن مبدا به بررسی انها پرداخته می شود.در قسمت ضمائم تحقیق واژه نامه ای برای اشنایی خوانندگان با لغات و اصطلاحات حقو...
Targeted Therapy in Ewing Sarcoma
Despite marked improvement in the prognosis of patients with nonmetastatic Ewing sarcoma (ES), the outcome for patients with recurrent or metastatic disease remains poor. Insight into key biologic processes in ES could provide new therapeutic targets. The particular biologic feature of ES, the fusion of the EWS gene with a member of the ETS family of genes, is present in >95% of cases. The EWS-...
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ژورنال
عنوان ژورنال: Clinical Cancer Research
سال: 2014
ISSN: 1078-0432,1557-3265
DOI: 10.1158/1078-0432.ccr-13-0633